Summary of Evidence - Vasomotor symptoms

Vasomotor symptoms are the most common menopausal symptoms in women after breast cancer and include hot flushes and night sweats.

Thirty-nine studies (36 RCTs with three updated analyses or sub-studies) out of the 45 studies included in the primary systematic review reported on management of vasomotor symptoms in women with a history of breast cancer. Of these studies, all assessed the frequency, severity and/or problems/bother of hot flushes, with four trials also reporting on sweating and/or night sweats.

Twenty two systematic reviews and five RCTs identified in the supplementary Evidence Review reported the effect of one or more interventions on vasomotor symptoms.