Hormonal treatment for infertility

Inconclusive: The evidence is too limited to determine the likelihood of an association with increased or decreased risk of endometrial cancer.

There is no conclusive evidence that taking drugs to increase fertility* is associated with an increased risk of endometrial cancer. Studies have been of poor quality.

Any change seen in the risk of endometrial cancer in women who use fertility drugs is likely to be due to the underlying reasons for infertility, such as ovulatory disorders and obesity, rather than use of the drugs.

*Fertility drugs are drugs used to stimulate the activity of the ovaries. They include a group of drugs called ‘selective oestrogen receptor modulators’ as well as drugs used during in-vitro fertilisation (IVF).