One prospective study (Niwinska 2010) assessed outcomes in HER2-positive breast cancer patients with occult brain metastases compared with patients with symptomatic brain metastases.110 Occult brain metastases were detected in 36% of the screening group. The median time between recurrence (distant and/or locoregional) and the diagnosis of occult brain metastases was 9 months.110 Twenty-six patients were given WBRT, with 24 patients available for assessment of radiological response. At three months follow-up, MRI found that 29% of patients were in complete remission, 63% were in partial remission, and there was no change in the brain for 8%. At the time of analysis, complete remission was maintained for two of the five survivors.110
Cancer Australia was established by the Australian Government in 2006 to benefit all Australians affected by cancer, and their families and carers. Cancer Australia aims to reduce the impact of cancer, address disparities and improve outcomes for people affected by cancer by leading and coordinating national, evidence-based interventions across the continuum of care.
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