People with lymphoedema are prone to recurrent episodes of cellulitis, and urgent antibiotic treatment is essential to control the spread of the infection.


Recommended antibiotics are:

  • dicloxacillin or flucloxacillin
    500mg orally, every 6 hours, for 7–10 days, or
  • clindamycin (for patients allergic to penicillin)
    450mg orally, every 8 hours.


Patients should be advised to:

  • rest in bed and elevate the affected body part
  • continue using their compression garment, if comfortable and tolerable
  • cease lymphatic drainage until the cellulitis has resolved.

Recurrence of cellulitis

In cases of frequent recurrence of cellulitis, consider continuous prophylaxis – the recommended plan is:

  • phenoxymethylpenicillin
    250mg orally, twice daily, for 6 months initially.